patented fusion for sustained energy & fat burning









Patented Buffered Caffeine

A Fusion of Nature & Science

Named “Breakthrough Product of the Year”
by Success Magazine

Featured on the front page of the
Wall Street Journal



Buffered Caffeine™ is the only Buffered Caffeine that negates the fat-storing and blood glucose imbalances caused by ingesting caffeine and caffeine-drinks.

Buffered Caffeine™ is a Patented EDIBLE COMPUTER CHIP® that programs the body to burn fat and to create maximum energy, instead of storing fat into adipose tissue fat cells.

Energy drinks and caffeinated beverages can cause fat-storage and weight gain. The only methodology for blunting that effect is Buffered Caffeine™.




Bio-Engineered Caffeine


Buffered Caffeine™ was designed by leading Glycemic Index Researchers

Why is it important to have glycemic researchers design an energy drink?

Because energy drinks cause FAT-STORAGE in humans. What is the point of energizing the body and stimulating fat-storage at the same time?

The only way to engineer an energy drink that does not stimulate fat-storage is to incorporate the Glycemic Index (www.Glycemic.com) and the Cephalic Response (www.CephalicResearch.com) into the equation and to use Buffered Caffeine instead of regular caffeine.





Biochemical Mechanism


Biochemical Actions of
Buffered Caffeine™

Research & Science


Thermogenic Fat-Burning
High Energy Levels
Blunts the Fat-Storing effects of Caffeine
Certified Low Glycemic Energy Matrix
Combats Stress-Related Eating
Patented Hunger Control
The Only Non-Cephalic Buffered Caffeine


PATENTED CORE COMPOUND

The Buffered Caffeine Patented Core Compound, known as Buffered Caffeine™, is comprised of Buffered Caffeine, Chromium, and a specifically designed Low Glycemic, Non-Cephalic Carbohydrate, known as Sweet Infused Fruits™.

The Buffered Caffeine™Edible Computer Chip® was designed to be implanted (added) to any beverage, energy drink, fat-burning drink, thermogenic drink, weight management product, protein drink, and other products, for the purpose of creating maximum adipose tissue (white and brown fat cells) fat-burning and maximum glycemically balanced energy in humans.


WHAT IS AN EDIBLE COMPUTER CHIP®?
www.EdibleComputerChips.com


PATENT PROTECTION:
BACKED BY A FULL U.S PATENT

No other product can legally contain Caffeine or guarana, any form of chromium, including picolinate, polynicotinate, or yeast-chromium, with a Low Glycemic Carbohydrate without violating our broad Patent. The Buffered Caffeine Patent has been also been awarded for use in any beverage, including coffee, tea, soda, cola, flavored/enhanced water, and sports drinks.


OTHER CAFFEINE-BUFFERS

There are currently (2009) no other Buffered Caffeine products or Patents that buffer caffeine’s proclivity to increase adipose tissue fat-storage, elicit weight loss, block Cephalic Insulin Response, and moderate glycemic response.


PATENT AWARDS

The Buffered Caffeine™ Patent was named “Breakthrough Product of the Year” by Success magazine, and was featured on the front page of the Wall Street Journal for having generated over $ 300 Million Dollars.


SWEET INFUSED FRUITS™

The Low Glycemic Carbohydrate utilized in Buffered Caffeine™ is 100% natural Sweet Infused Fruits™.

www.SweetInfusedFruits.com




Clinical Research

Patented Buffered Caffeine

The following research projects have been conducted on Buffered Caffeine™ via Board Certified Human In Vivo Clinical Trials.



Cellular level thermogenesis, caffeine and DIT, methods for buffering caffeine to eliminate fat-storage in fat cells, caffeine thermogenesis
Identify and quantify Pathogenesis of Obesity and Diet-Induced-Thermogenic agents in humans
Thermogenic and fat-storing response of carbohydrates, sugars and sweeteners, stimulation of fat-storing enzymes in humans, Brown Adipose Tissue (BAT) and thermogenesis
Internal vs DIT thermogenesis, thermogenic capacity of cells and tissues, UCP in mitochondria, Resistin, lipolytic actions in humans, appestat centers of the brain
Identification and reduction of fat cell mass in humans, caloric conversion info fat cells, human genetic code related to deposition of adipose tissue body fat, N.E.A.T., fat thermostat in humans, hypothalamus-related fat-storage
LPL gatekeepers for fat-storage in the fat cell, chromium and thermogenesis, high-protein diets and reduced thermogenesis, aging and adipose tissue fat accumulation, adipocyte lineage, regulation of beta-3-adrenoceptor expression in white vs brown fat cells



Scientific Data

Sweet Infused Fruits™

Board Approved Human In Vivo Clinical Trials
2008-2009


Sweet Infused Fruits™ provides the base for Buffered Caffeine™ which provides the Pathobiochemical Blunting Mechanism for Dietary induced Thermogenesis (DIT).

Sweet Infused Fruits™ have been clinically proven to act as an Anti-Carbohydrate in humans, preventing the shunting of caffeine-beverages into adipose tissue fat cells.


Sweet Infused Fruits ™ have undergone numerous Board Approved Human In Vivo Clinical Trials in adults, children, and diabetics:

Sweet Infused Fruits ™ are Certified Low Glycemic, and have been clinically proven not to stimulate human Adipose Tissue Fat-Storage.
Sweet Infused Fruits ™ are an important tool in the Obesogenics epidemic.
Sweet Infused Fruits ™ do not activate primary Lipoprotein Lipase human fat-storing mechanisms, and does not elevate blood glucose or insulin levels in non-diabetics and type 2 diabetics.
Sweet Infused Fruits ™ have been shown to act as an “Anti-Carbohydrate” in clinical trials.

CLINICAL TRIALS

Sweet Infused Fruits ™ have been proven to act as an Anti-Carbohydrate in six (6) separate Human In Vivo Clinical Trials; Adult Diabetics, Adult Non-Diabetics, and Children under 17.

The term Anti-Carbohydrate ™ has been assigned to Sweet Infused Fruits™ due to their unique ability to mitigate, block, and prevent the typical metabolic reaction as related to every known carbohydrate, and as opposed to all other carbohydrates.

Sweet Infused Fruits ™ have been shown to be capable of reversing the known and proven responses to high glycemic foods, with benefits in post-prandial blood glucose, insulin, and adipose tissue fat-storage via Lipoprotein Lipase.

Small doses of Sweet Infused Fruits ™ (7-8 g) consumed 30 or 60 minutes prior to consuming a high glycemic index (50 g/carb), starchy food decreases the glycemic response compared with either immediate or no Sweet Infused Fruits ™ treatments.

Further, this same dose of Sweet Infused Fruits ™ (7-8 g) reduces the glycemic response to a very large volume of an extremely high glycemic (75 g/carb beverage, soda, or sports drink.

Sweet Infused Fruits ™, unlike high glycemic sweeteners and sugars, does not stimulate insulin secretion from pancreatic ß-cells. Physiological sensing of plasma glucose is primarily elucidated at the level of the pancreatic ß-cell.

These findings provide practical applications as the small amount of Sweet Infused Fruits ™ required for this response can easily be supplied as an adjunct to the diet.

CLINICAL TRIALS # 1 - 4
Sweet Infused Fruits ™ acutely and significantly mitigates blood glucose and glycemic responses, and fat-storage properties of oral ingestion of ice cream in humans.

CLINICAL TRIAL # 5
Sweet Infused Fruits ™: Mitigation of adipose tissue fat-storage, blood glucose and glycemic responses, Lipoprotein Lipase, and insulin resistance in reaction to oral ingestion of chocolate candy in humans.

CLINICAL TRIAL # 6
Sweet Infused Fruits ™: Mitigation of the diabetic, glycemic and metabolic responses in humans associated with oral ingestion of Glucosamine, a known diabetic-risk-agent.

INSULIN & PRE-DIABETES IN CHILDREN:
INSULIN RESISTANCE


In 2008, renowned Pediatrician, Dr. William Sears*, stated “Carbs are Killing our Children.” Dr. Sears describes Pre-Diabetes in children as Insulin Resistance, and has seen “narrowing of the arteries in children as young as 3-years old, with insulin levels of 38.

Normal insulin levels range from 11-19. The upper limit insulin level is 29. In children who are Pre-Diabetic, insulin levels reach as high as 38.

The Pre-Diabetic stage is the precursor to full blown type 2 diabetes and personifies Insulin Resistance. During this stage of insulin imbalance, the body has lost the ability to process sugar and high glycemic carbohydrates, and there is not enough insulin to help the sugar get into the cells and use it as energy. When this occurs, the sugar/carbohydrate goes into storage (fat cells) instead of being utilized as an energy fuel.

Repeated consumption of foods and beverages that stimulate this response leads to obesity and type 2 diabetes in children and adults. The obesity and Insulin Resistance epidemic in children keeps escalating with no end in sight. As long as children continue to consume foods and beverages that elevate insulin levels and blood glucose levels, the plight will continue.

Source: Dr. William Sears, Associate Clinical Professor of Pediatrics, University of California, Irvine, Harvard Medical School, Children's Hospital ((Boston), The Hospital for Sick Children (Toronto); Associate Ward Chief of Newborn Nursery and Associate Professor of Pediatrics.

INSULIN RESPONSE OF SWEET INFUSED FRUITS™

Unlike glucose and other sugars, Sweet Infused Fruits ™ do not stimulate insulin secretion. In clinical trials, “Orally ingested and IV administered SIF were ineffective in eliciting postprandial insulin secretion.”

DIABETIC APPLICATIONS

Sweet Infused Fruits ™ do not elicit a Cephalic Insulin Response in humans, and do not stimulate insulin secretion in humans. SIF are Low Glycemic, Non-Insulin-Cephalic, with a Low Glycemic Load.

Therefore, Sweet Infused Fruits™ may be used in Type 2 diabetic formulations, including meal replacement drinks and bars, medical feeding formulas, low glycemic ice cream and candies, diabetic candies, caffeine-products and beverages, and products for diabetic children.

Sweet Infused Fruits ™ have been demonstrated to serve as a useful role in the dietary management of blood sugar levels, since substitution of Sweet Infused Fruits ™ for other simple carbohydrates should lead to reduced post-prandial glucose levels that will aid in overall control.

In persons with type 2 diabetes, the requirement for insulin is greater than that produced by the pancreas. Sweeteners that produce a lower secretion of insulin and blood glucose are known to be beneficial for glucose metabolism.

RESULTS & BENEFITS


Stimulation of Lipoprotein Lipase (LPL) increases weight gain, obesity, type 2 diabetes, and insulin-resistance.

LPL is the "Gatekeeper for fat-Storage in the fat cell.” High glycemic and High-Cephalic ingredients, foods and beverages stimulate LPL.

Abdominal fat Lipoprotein Lipase (LPL) activity contributes to the increased risk for developing obesity-associated diseases.

The leptin content of fat depots as well as plasma insulin concentrations appear in our population as the main determinants of adipose tissue LPL activity, adjusted by gender, depot and BMI.


In type 2 diabetics, consuming 60 grams of Sweet Infused Fruits™ as compared to a typical diabetic meal (for 12 weeks) resulted in decreases in both serum glucose (SG) and glycated hemoglobin concentrations (GHC), which progressively decreased in the group treated with Sweet Infused Fruits™ (SIF). In the control group not using SIF, both SG and GHC increased.
Oral ingestion of Sweet Infused Fruits™ blunts LPL activity and results in improvements in glycemic control and alterations in apoprotein composition, which decrease risk of obese, diabetic, and coronary events in humans.
Utilizing low glycemic sweeteners and carbohydrates, such as Sweet Infused Fruits™, that do not stimulate blood glucose and insulin levels, and do not trigger LPL, are essential in the long-term prevention of obesity in humans.
THERMOGENIC EFFECT: When ingested, more energy is required to metabolize Sweet Infused Fruits™, thus this process burns up more calories.
SATIETY: It has been demonstrated that consumption of Sweet Infused Fruits ™ prior to eating is particularly effective at preventing hunger pangs and promotes a reduction in calorie consumption during the meal itself. Eating snacks and drinks containing Sweet Infused Fruits™ could help the weight conscious and the clinically obese adhere to calorie-controlled diets.
ENERGY DRINKS & SPORTS DRINKS: The Low Glycemic properties of Sweet Infused Fruits™ (SIF) provide an ideal base for sports drinks and sports products, as they help provide a sustained source of energy, and do not cause reduced-sports-performance. In energy drinks, SIF blunt adipose tissue fat-storage instigated by caffeine and caffeinated-beverages, blunts LPL activity and results in improvements in glycemic control and alterations in apoprotein composition, which decreases risk of weight gain, obesity, and diabetes in humans.
GLYCEMIC CONTROL: With its Low Glycemic Index and Load, Sweet Infused Fruits™ can be consumed to improve glycemic control. Sweet Infused Fruits™ have very little effect on blood glucose and a negligible effect on the secretion of insulin.
The use of low glycemic sweeteners, such as Sweet Infused Fruits™, further improves short and long-term treatment of obesity and type 2 diabetes.
Reducing the use of high glycemic carbohydrates, sugars, and sweeteners improves incidence, risk, and development of obesity and type 2 diabetes.
Sweet Infused Fruits™ enhance mineral absorption and this offers considerable benefits, not only for the general population, but also for special groups such as pregnant women who require increased levels of minerals, especially iron and calcium.

Copyright® 2008-2009
www.SweetInfusedFruits.com





Buffered Caffeine
Certifications


Buffered Caffeine™ has been independently Certified by:






Glycemic Research Institute®


License Issued and Authorized by:
U.S. Government Certification Program
United Kingdom Certification Program
Canada Government Certification Program

www.Glycemic.com





Skinny Science®
www.SkinnyScience.com






Human Sports Performance™

Certified Safe for Athletes
Meets the Guidelines of the U.S. Olympic Committee & the World Anti-Doping Agency

www.HumanSportsPerformance.com








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These statements have not been evaluated by the Food & Drug Administration. The products promoted herein are not intended to diagnose, treat, cure, or prevent any disease.


 

Copyright © 2008-2010 Buffered Caffeine™